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Medicine · Erectile Dysfunction

Avanafil | Brands, Strengths and Prices

Avanafil is a prescription-only PDE5 inhibitor, sold as Stendra in the US and Spedra in the UK and Australia, used to treat erectile dysfunction.

Anjali K. Iyer, B.Pharm, medical content reviewer Reviewed by Anjali K. Iyer, B.Pharm 3 products Prescription required. A pharmacist checks every order.
Brand nameSpedra (UK, AU), Stendra (US)
Drug classPDE5 Inhibitor
Controlled Substance ClassificationNot a controlled medication
Generic StatusGeneric versions available
AvailabilityPrescription only

Check out our range of avanafil products, which includes Avana 200mg, Avana 100mg and Avana 50 mg.

All these medications are composed of the same ingredient, i.e avanafil, but differ in form, manufacturer and strength. These medications are only used for erectile dysfunction.

Avanafil brands and prices

Brand Strength Form Price from Link
Avana 50 mg Sunrise Remedies 50 mg Tablet $175.00 90 Tablets View
Avana 100 mg Sunrise Remedies 100 mg Tablet $229.00 90 Tablets View
Avana 200 mg Sunrise Remedies 200 mg Tablet $289.00 90 Tablets View

What is avanafil?

Avanafil, the generic for Stendra (US) and Spedra (UK and AU), is a prescription-only medicine used to address male sexual dysfunction known as erectile dysfunction. This medication should be used only with proper consultation from a doctor.

How does avanafil work?

Avanafil is a PDE5 inhibitor. It helps maintain erectile function by sustaining levels of cyclic guanosine monophosphate (cGMP) in penile tissue [1]. It results in prolonged smooth muscle relaxation, increased blood flow, and the maintenance of an erection during sexual stimulation. Its rapid onset and targeted action make it a valuable option for men seeking treatment for erectile dysfunction.

Avanafil does not work

  • Against sexually transmitted infections (STIs)
  • In preventing pregnancy

What is avanafil used for?

Avanafil is used as a treatment for adult men with erectile dysfunction. Erectile dysfunction is a health condition in which the penis does not harden and expand when a man is sexually aroused, or is unable to keep an erection.

Avanafil is used to support increased blood flow within the penis when appropriate stimulation occurs.

How quickly does avanafil work and how long does it last?

15–30 minto start working
Up to 6 hourshow long it usually lasts
Once a daymaximum dosing frequency

It usually starts working within 15 to 30 minutes after taking it; however, the onset may vary between individuals. It works only when sexual stimulation is present. Avanafil works best on an empty stomach, while a high-fat meal may delay the effect [2].

Avanafil usually lasts up to 6 hours, although duration may vary by individual. This does not mean a man should have a continuous erection if used for erectile dysfunction. Follow the prescribed dosage, and do not take more than the recommended amount within 24 hours.

Dosage, strengths and forms

Our product range includes Avanafil-based medicines in different strengths as tablets. The products are: Avana 50mg, Avana 100mg, and Avana 200mg.

Available Products and Forms

ProductForm
Avana 50mgFilm-coated tablets
Avana 100mgFilm-coated tablets
Avana 200mgFilm-coated tablets

Dosage information

The recommended starting dose is 100mg. It is usually taken about 15 minutes before sexual activity [3].

Depending upon the individual's efficacy and tolerability, your doctor may increase the dose to 200 mg taken about 15 minutes before sexual activity, or decrease to 50mg taken about 30 minutes before sexual activity.

The maximum recommended dosage frequency is once per day. Follow the directions on your prescription label, and ask your doctor to explain anything you do not understand.

How to take avanafil

  • Avanafil comes as tablets; swallow the tablet whole with a full glass of water.
  • You may take Avanafil with or without meals; consult a healthcare professional before taking it.
  • Check the packaging or leaflet that comes with your medicine. Read and follow the instructions carefully. Ask your pharmacist or doctor if you have any questions.
  • Do not keep outdated medicine or medicine you no longer need.

Missed dose

Not applicable: Avanafil is an on-demand medication and is taken before planned sexual activity.

Do not exceed the maximum recommended frequency within a 24-hour period.

Overdose

Taking more than the prescribed dose of Avanafil may lead to overdose. Some of the signs of Avanafil overdose are:

  • Severe drop in blood pressure
  • Severe dizziness
  • Fainting
  • Prolonged erection lasting longer than 4 hours (priapism)

In case you suspect an overdose, seek medical attention.

  • USCall 911
  • UKNHS 111 or 999
  • AU13 11 26 Poisons Information or 000

Side effects

Below are the avanafil side effects that can cause adverse effects at times:

Common side effects

  • Headache
  • Flushing of the face
  • Nasal congestion
  • Back pain
  • Dizziness
  • Upset stomach
  • Sore throat

Get help if you experience

  • Allergic reactions - skin rash, itching, hives, swelling of the face, lips, tongue, or throat
  • Hearing loss
  • Pain or tightness in the chest, shoulders, arms, or jaw
  • Shortness of breath
  • Low blood pressure - blurry vision, feeling faint
  • An erection lasting longer than 4 hours and being painful
  • Sudden numbness
  • Trouble speaking, confusion, trouble walking

These are not all the side effects of avanafil. Check out the leaflet that came with your medicine or report adverse situations to the US FDA through the FDA MedWatch Program, the UK through the MHRA Yellow Card Scheme, or in Australia to the TGA.

Who should avoid Avanafil?

Avanafil should not be taken if you have -

  • An allergic reaction or serious side effects from avanafil
  • Kidney or liver problems
  • Non-arteritic anterior ischemic optic neuropathy or NAION (serious eye condition)
  • Abnormal penis, including curved penis and birth defects of the penis
  • Leukemia
  • Multiple myeloma
  • Sickle cell anemia
  • Recently had a heart attack (within the last 6 months)
  • Under 18 years old

Always inform your pharmacist about all your health conditions, including diabetes and hyperlipidemia (high fats in the blood).

Possible interactions

Do not take it with nitrates such as nitroglycerin, isosorbide dinitrate, or isosorbide mononitrate, or recreational drugs that contain nitrates called 'poppers' (such as amyl or butyl nitrite). If you combine these, it can cause a severe and potentially life-threatening drop in blood pressure.

Some medicines and supplements may not mix well with Avanafil and may cause drug interactions. This includes:

  • Riociguat or vericiguat (medications for pulmonary hypertension)
  • CYP3A4 inhibitors, such as ketoconazole, itraconazole, clarithromycin, ritonavir, and atazanavir
  • Macrolide antibiotics like clarithromycin, erythromycin, telithromycin
  • Phenobarbital
  • Phenytoin
  • Rifabutin, rifampin, or rifapentine
  • Alpha-blockers (such as tamsulosin)
  • HIV or AIDS medicine
  • Supplements containing St John's Wort
Food

Avoid grapefruit

Avoid grapefruit and grapefruit juice, as it can increase the risk of severe side effects.

Alcohol

Limit alcohol

Drinking moderate to large amounts of alcohol while taking this medicine can lower blood pressure and can make it difficult to achieve an erection.

Avanafil vs Sildenafil (Viagra)

Both Avanafil and Sildenafil (Viagra) are used to treat erectile dysfunction, but they differ in how quickly they start working. Below is the list mentioned:

Basis of DistinctionAvanafilSildenafil (Viagra)
Onset of action15 to 30 minutes30 to 60 minutes
Duration of actionUp to 6 hours4 to 6 hours
Food effectOnset slowed by heavy mealsOnset slowed by heavy meals
Daily optionNoNo

Avanafil in the US, UK and Australia

Below is the list of the brand name, supply and regulator of the three countries:

US

United States

Brand Name
Stendra
How it is supplied
Prescription only (Rx)
Regulator
FDA
UK

United Kingdom

Brand Name
Spedra
How it is supplied
Prescription-only medicine (POM)
Regulator
MHRA
AU

Australia

Brand Name
Spedra
How it is supplied
Prescription-only (Schedule 4)
Regulator
TGA

How to order avanafil online with a prescription

Below are the steps to order avanafil online with a prescription:

  1. Choose the dosage on your prescription that matches your medical condition.
  2. Upload the prescription that your healthcare professional provided for medical review.
  3. Our registered pharmacists will review your valid prescription and the medical information provided.
  4. After the review, our team will process the discreet dispatch of your package. You will receive a confirmation email after the dispatch. Delivery times are provided by country in the Shipping Policy.

How to order · Prescription policy · Shipping policy

Sources

  1. Avanafil - ncbi.nlm.nih.gov
  2. Avanafil - medlineplus.gov
  3. AVANAFIL - avanafil tablet - dailymed.nlm.nih.gov

Frequently asked questions

Where to buy avanafil?

Buy avanafil online at Prashi Pharma, an online pharmaceutical supply platform selling quality medications.

Can I buy avanafil over the counter?

No, you cannot buy avanafil over the counter. It is a prescription-only medication used to treat erectile dysfunction.

Is avanafil stronger than tadalafil?

Both avanafil and tadalafil are effective for erectile dysfunction. Avanafil and Tadalafil are phosphodiesterase-5 (PDE-5) inhibitors that work through similar core mechanisms; they differ mainly in how quickly they start working and how long they last.

How long will avanafil last?

Avanafil can last up to 6 hours, depending on the medical condition.

Can I buy avanafil without a prescription?

No. Avanafil is a prescription-only medication; consult a doctor and share your medical condition.

Is there a generic version of avanafil?

Avanafil is the generic name; Stendra (US) and Spedra (UK and AU) are brand names. Generic versions, such as Avana, have the same active ingredient and work to treat erectile dysfunction.

How should I store avanafil (generic Stendra)?

Keep avanafil at room temperature, away from excess heat and moisture. Keep out of reach of children and pets.

Is Avanafil effective for men who have had prostate surgery?

If you have undergone a prostatectomy or other prostate surgery, consult a healthcare professional before taking Avanafil.

What should I do if Avanafil does not work for me?

If Avanafil does not seem to work for you, do not increase your dose or take another tablet on your own. Many factors can affect how well it works, and your doctor may need to adjust your treatment plan. Consult with your doctor first.

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